12 Mar S4 (Andarine) – Don’t Buy Until You Read This 2020 Inspection
Andarine, commonly known as S4 on the current market, comes under the umbrella of a broad group of drugs called SARM (Selective Androgen Receptor Modulator), however, S4 is considered to be more potent and valuable when compared to other similar SARMs like LGD-4033. It was initially made by GTX labs throughout its research aiming for remedies of senile- onset muscular wasting disorders like muscular dystrophy, osteoporosis and benign enlargement of the prostate.
It has shown promising results during creature trials and now, numerous medical research groups are running various human trials to elicit more beneficial effects on skeletal muscle mass, strength and bone density. Even though S4 has been yet to be prescribed by practitioners, it is widely included in the body exercise regime of aspiring athletics. Moreover, the selectivity of the drug removes numerous side effects than traditional steroids bring.
Mechanism of Action
Similar to other SARMs, Andarine has a greater affinity to androgen receptors, the frequent site of action of male sexual hormone- testosterone. While conventional synthetic steroids bind to androgen receptors indiscriminately, SARMs are very specific in its manner of action, affecting just those existing in skeletal muscles and bones. Undoubtedly, this selectivity gives Andarine an edge more than steroids. A number of the remarkable benefits of Andarine include growth in lean muscle mass, lipolysis and fostering of stamina and strength.
Since a large number of researches are moving around regarding S4, forms of advantages have been reported worldwide. A number of these are listed below.
- The bioavailability of Andarine is quite large instead of other SARMs. This implies Andarine is very potent and also a smaller dose is sufficient to exhibit significant added benefits. Additionally, according to research journals, Andarine does not undergo aromatization (the process of conversion of testosterone into estrogen). This eliminates the danger of estrogenic side effects such as water retention, hair loss, gynecomastia.
- S4 increases the discharge of testosterone, and by doing this it helps to improve the energy level, enhancing endurance and strength.
- Improvement in metabolic activity enhances the growth in muscles and weight reduction.
- Although reports have suggested there is a slight suppression in natural testosterone levels, there is no related user report on this. The suppression could be potentially due to its anabolic activity but researchers claim that lower doses do not cause severe hypothalamic-pituitary suppression and there’s not any demand for a PCT (post cycle therapy).
Role In The Fitness Sector
S4 is remarkably popular with sports for ‘cutting edge’ and ‘bulking’ purposes. Despite less consumption of users have demonstrated to boost strength and muscle mass. Within a short span of time, you can raise your training hours in the gym without feeling tired. Andarine promotes fat oxidation and reduces lipoprotein lipase activity. This reduces fat accumulation and helps maintain their fat but converting the stored fats to fresh muscle tissues. All these are the characteristics required by fitness freaks, athletics and bodybuilders. Some may want to stack S4 along with different SARMs for synergic action.
Effects On Reproductive System
Studies have shown S4 to be selective to prostrate and may be clinically valuable in treating benign prostate hyperplasia (normally happening in older men). S4 does this by inhibiting dihydrotestosterone to bind to the androgen receptors and assists in the treatment of BPH.
Treatment of Osteoporosis and Degenerative Diseases
Owing to its capacity to prevent muscle wasting, S4 might be a potential choice for treating senile-onset osteoporosis. This is a disease found in older post-menopausal girls where pathological fractures are very common. There’s an imbalance in bone formation and bone degeneration. Andarine increases bone mineral density and improves the bone matrix, increasing strength and endurance.
Aids In Weight Loss
In today’s modern world, obesity is now the main concern due to unhealthy lifestyle choices and lack of physical activity. When a sedentary lifestyle is prevailing, exercise is becoming old-fashioned. Even with a balanced low-calorie diet, promoting fat loss remains an exhausting task. With Andarine, there’s an increase in the metabolism of human anatomy which not just promotes fat loss but the gain of lean muscle mass, but significantly provides the ideal body shape which most professionals, such as athletics, versions, therapists desire.
Even though the suppressive action on the pituitary gland of Andarine isn’t prominent, like any other medicinal compounds, this drug reported to have milder side effects. However, male breast augmentation increased blood pressure, hair loss, the appearance of manly traits in females and hepatotoxicity are not seen with SARMs, owning to their particular action on muscles and bones.
Together with Andarine, users have reported problems of seeing little yellow dots with problems to vision in dim light. This is because the S4 molecule binds to receptors in the retina. Users usually note that during the night, while going from dark to bright areas. But this effect is reversible and immediately disappears when users stop the drug.
Dose Program and Half-Life
According to recent research, Andarine includes a brief half-life of about 3-4 hours. However, this medication is so potent and effective that low doses are adequate. The suggested dose is to start from 25mg up to your maximum dose of 50mg daily. However, female users should begin at a lower dose. Normally, one cycle should last for 8-12 weeks. Users can divide the dose per day and evening sessions with snacks according to desire.
Doping and WADA
Since the last 10 years, wise spread accessibility of SARMs has been decreased due to prohibition by the US Anti-Doping Agency (USADA) and the World Anti-Doping Agency (WADA). This is because users of SARMs possess an unfair edge over non-users if they’re into competitive sports.
In brief, Andarine is a promising medication for the treatment of osteoporosis and muscle-wasting along with a huge quantity of benefits in medication but research work is still undergoing. Though WADA has banned the use of the drug among sports, sales of the drug have peaked internationally in recent years for building muscles, enhancing endurance and accelerated weight loss. Users can observe the substantial changes in a form after 2 weeks of usage.